2022 March Madness predictions: NCAA bracket expert picks against the spread, odds in Saturday's Round 2 games (2024)

The college basketball marathon is far from over, and have already jumped right into the weekend action. The First Round festivities closed on Friday night and Second Round play in the 2022 NCAA Tournament will get started beginning Saturday with a field half as big as the one that was in it ahead of Round 1. Over the next few days, the bracket will again eliminate half the field as it goes from 32 to a Sweet 16, setting up the second weekend of this year's tournament.

If this tournament has taught us anything so far, it's that Saturday's slate should provide us with drama. We've already had several overtime games, some Cinderella candidates have emerged, and upsets have thus far been plentiful. Round 2 action features six single-digit spreads out of eight games, so as the bracket continues to unfold, oddsmakers are expecting more close contests to continue.

To get you prepped for the first day of Round 2, I've called on our experts together to make picks straight up and against the spread to help you pick your bracket (and hopefully make some cheddar along the way). You can also check our expert brackets.

LIVE updates:Follow all the scores, highlights and analysis in the Second Round on Saturday.

Be sure to stick with CBS Sports throughout the rest of the month for NCAA Tournament coverage through the end of the Final Four. Let's take a look at our expert picks for the final slate of second-round games on Saturday.

Odds via Caesars Sportsbook | All times Eastern

NCAA Tournament: Round 2 picks

(1) Baylor vs. (8) North Carolina

Saturday, 12:10 p.m. | CBS, March Madness Live: Baylor may be the most vulnerable of all the No. 1 1 seeds in this year's tourney -- it remains without leading scorer LJ Cryer and glue guy Jonathan Tchamwa Tchatchoua because of injury -- but I'm still laying the points here with the Bears. They have the personnel to limit Brady Manek and Armando Bacot and match up well in the backcourt thanks to a veteran bunch led by Adam Flagler and James Akinjo. Pick: Baylor -5.5


ParrishNorlanderPalmBooneCobbPatterson

Spread

UNC +5.5

BAY -5.5BAY -5.5
BAY -5.5
UNC +5.5
UNC +5.5

Straight up

BAY

BAY
BAY
BAY
UNCUNC

(1) Kansas vs. (9) Creighton

Saturday, 2:40 p.m. | CBS, March Madness Live:Creighton was fortunate to escape in Round 1 in overtime against a San Diego State team that led nearly the entire game. It won't have the luxury of playing with fire against Kansas, though, and I don't envision it will get a chance to do that, either. KU's starting to fire on all cylinders with Remy Martin stepping up to play a key role next to star Ochai Agbaji in the backcourt. Jayhawks should cruise to a comfortable win.Pick: Kansas -11.5


ParrishNorlanderPalmBooneCobbPatterson

Spread

KAN -11.5

KAN -11.5
KAN -11.5
KAN -11.5
KAN -11.5
KAN -11.5

Straight up

KAN

KAN
KAN
KAN
KAN
KAN

(3) Tennessee vs. (11) Michigan

Saturday, 5:15 p.m. | CBS, March Madness Live: Since a blowout loss to Kentucky on Jan. 15, Tennessee has the No. 2 defense in the country and a No. 25 offense to complement it, according to Bart Torvik data. The Volunteers since then have won 16 of 18 and are coming off a 29-point blowout win of Longwood in Round 1. The six-point spread is well within reach for them to cover against a Michigan team that had some struggles in Round 1 vs. Colorado State.Pick: Tennessee -6


ParrishNorlanderPalmBooneCobbPatterson

Spread

TENN -6

TENN -6
MICH +6TENN -6
TENN -6
MICH +6

Straight up

TENN

TENN
TENN
TENN
TENN
TENN

(4) Providence vs. (12) Richmond

Saturday, 6:10 p.m. | TNT, March Madness Live: Providence made a statement in its first-round win over South Dakota State, the top 3-point shooting team in the country, by yucking up the game with physicality and limiting the Jackrabbits' strengths. The Friars know how to play out a scouting report. So, this game should favor them by a smidge, but I'm taking the points with Richmond, which is on a tear after winning four games in four days in the Atlantic 10 tourney and just knocked off arguably the hottest team in the sport in Iowa. This Spiders team is rolling with Jacob Gilyard riding a heater, and I'm ready to ride the wave with them.Pick: Richmond +3


ParrishNorlanderPalmBooneCobbPatterson

Spread

PROV -3

PROV -3
PROV -3
RICH +3RICH +3
RICH +3

Straight up

PROV

PROV
PROV
PROV
PROV
RICH

(4) UCLA vs. (5) Saint Mary's

Saturday, 7:10 p.m. | TBS, March Madness Live: UCLA played with fire a bit against Akron in Round 1 after uncharacteristically inefficient outings from both Jaime Jaquez Jr. and Johnny Juzang. I'm expecting bounce-back showings from both in this one to cover the points. Gaels have the goods to keep this close throughout, and I expect they will, but UCLA's talent and tourney experience eventually will win out.Pick: UCLA -2.5


ParrishNorlanderPalmBooneCobbPatterson

Spread

UCLA -2.5

SMC +2.5SMC +2.5
UCLA -2.5
SMC +2.5
SMC +2.5

Straight up

UCLA

SMCSMC
UCLASMC
SMC

(7) Murray State vs. (15) Saint Peter's

Saturday, 7:45 p.m. | CBS, March Madness Live: Call me a sucker for a good story -- I'm a writer, sue me! -- but I like the Peaco*cks of Saint Peter's to cover against Murray State and maybe they even replicate their magic from Round 1 when they upset No. 2 seed Kentucky. Maybe they don't, but the scoring punch of Daryl Banks III and Doug Edert in the backcourt is enough firepower to keep it within the number even against a Murray State team that has not lost since Dec. 22.Pick: Saint Peter's +8


ParrishNorlanderPalmBooneCobbPatterson

Spread

SPC +8

MURST -8MURST -8
SPC +8
SPC +8
MURST -8

Straight up

MURST

MURST
MURST
MURST
MURST
MURST

(4) Arkansas vs. (12) New Mexico State

Saturday, 8:40 p.m. | TNT, March Madness Live: Teddy Allen's 37 points willed New Mexico State to a first-round upset of UConn, but on two days rest after playing 39 of 40 minutes, can he play superhero again? I'm skeptical the underdog Aggies do it back-to-back. This Arkansas team has a respectable defense that's going to strategically try to take the ball out of Allen's hands and throw enough defenders at him to make him really work, too. New Mexico State keeps things within the number, but Arkansas wins something like 71-66.Pick: New Mexico State +6.5


ParrishNorlanderPalmBooneCobbPatterson

Spread

NMST +6.5

NMST +6.5

ARK -6.5

NMST +6.5

NMST +6.5

NMST +6.5

Straight up

ARK

NMST

ARK

ARK

NMST

ARK

(1)Gonzagavs. (9)Memphis

Saturday, 9:40 p.m. | TBS,March Madness Live:The combination of Gonzaga's early struggles in Round 1 and Memphis' late-season surge -- culminating with a cozy Round 1 win overBoise State-- should make the Zags-Tigers game a must-watch finale on Saturday. But the top overall seed hit a new gear in the second half of the first round and with the star power ofChet HolmgrenandDrew Timme, I'm laying the points here expecting it can pick up where it left off on Thursday.Pick: Gonzaga -10.5


ParrishNorlanderPalmBooneCobbPatterson

Spread

MEM +10.5

ZAGS -10.5

ZAGS -10.5

ZAGS -10.5

MEM +10.5

ZAGS -10.5

Straight up

ZAGS

ZAGS

ZAGS

ZAGS

ZAGS

ZAGS

Who will win every college basketball game, and which teams will sink your bankroll?Visit SportsLine now to see how to pick the spread, money, line, and over-under in each tournament game, all from the model that's up almost $1,500 on top-rated college basketball picks and simulates every possession 10,000 times.

2022 March Madness predictions: NCAA bracket expert picks against the spread, odds in Saturday's Round 2 games (2024)

FAQs

Who is the most accurate predictor for March Madness? ›

Heat Check CBB's Lukas Harkins is one of the most accurate bracketologists in all of college basketball media. Harkins has seven total years of experience in March Madness projections, consistently providing updated bracket predictions, team analysis, and “bubble watch” deep dives.

What are the odds of predicting a March Madness bracket? ›

The NCAA said the odds of a perfect 63-game bracket can be as high as 1 in 9.2 quintillion. Those odds are in play if every game was a coin flip – or a fair 50/50 shot. The amount of different possible outcomes comes out to exactly 9,223,372,036,854,775,808, according to the NCAA.

What's the closest someone has gotten to a perfect bracket? ›

According to Mike Benzie of NCAA.com, the closest anyone has gotten in the last decade occurred in 2019, when an Ohio man picked the first 49 games correctly. No one got nearly that close this season, as every bracket had at least one blemish before the first round ended Friday.

Who is favored to win March Madness 2024? ›

2024 March Madness odds: UConn favored over Purdue in men's title game. And then there were two. Now that we are down to the last two teams, the defending champion UConn Huskies remain the favorites to win the men's college basketball national title.

How accurate is bracketology? ›

“Historically, people are about 70% correct in bracket predictions. This makes your odds of a perfect bracket 1 in 5.7 billion.

What is the best bracketology website? ›

Delphi Bracketology has been ranked consistently in the top of the BracketMatrix rankings of all bracketologists in the country.

Has anyone ever guessed the entire March Madness bracket? ›

NO ONE HAS EVER picked a verified perfect NCAA men's bracket, and it's probably not going to happen in our lifetime, or the lifetime of our kids, or their kids, or their kids.

How often does someone get a perfect March Madness bracket? ›

That run of 49 correct games will be very hard to top in the future. The odds of a perfect 63-game NCAA bracket can be as high as 1 in 9.2 quintillion — though those are the perfect bracket odds if every game was a 50-50 coin flip.

How to pick the best bracket? ›

Then the case went sideways.
  1. Don't start filling out your bracket with Round 1; start with the Elite Eight or Final Four.
  2. Look for value in the Elite Eight.
  3. Be selective picking upsets.
  4. The size of your pool will tell you how much risk to take.
  5. Don't buy into the 12-seed mystique. ...
  6. Believe in at least one 'First Four' team.
Mar 18, 2024

Who was the first perfect bracket ever? ›

Greg Nigl of Columbus, Ohio, set the NCAA Tournament bracket record in 2019. He correctly predicted the winner of the first 49 games, breaking the previous record of 39 set in 2017 and becoming the first person to carry a perfect bracket past the second round.

Has anyone ever won March Madness back to back? ›

Seven different college basketball programs have won back-to-back national championships: Oklahoma State, Kentucky, San Francisco, Cincinnati, UCLA, Duke, Florida, and UConn.

What is the best bracket in March Madness history? ›

2017. Before Nigl shattered the record in 2019, one Yahoo bracket had set the pace for the most games unscathed in March Madness. One bracket got the first 39 games correct, but the run came to an end when Purdue beat Iowa State.

How likely is UConn to win March Madness? ›

2025 NCAA Tournament championship odds
UConn+1000
Ohio State+6000
UCLA+6000
Rutgers+8000
Michigan+8000
142 more rows
Apr 9, 2024

Who is most likely to win men's March Madness? ›

March Madness Power Rankings: Final Four
  • T-3) North Carolina State Wolfpack (+1600) In the never-ending fight against fate, destiny always wins. ...
  • 2) Purdue Boilermakers (+205) Basketball may very well be the most superstar-driven sport in the world. ...
  • 1) UConn Huskies (-195)
Apr 2, 2024

Who's favored to win the NCAA championship? ›

NCAA Tournament odds, futures: UConn still the betting favorite to win national championship.

March Madness bracket predictions: Expert ...Sporting Newshttps://www.sportingnews.com ›

The 2022 NCAA Tournament is finally upon us. The first round of March Madness matchups will begin Thursday, which means you have just hours to submit a bracket ...
Need help filling out your NCAA Tournament bracket? Our bracket guide has you covered with full details on when and where to pick upsets.
ALEXANDRIA, Va. — March Madness is here and college basketball experts near and far are sharing their predictions for the big dance. But have you thought about ...

What is the best website for March Madness research? ›

BracketResearch.com - Best Analysis and Predictions for the NCAA Basketball Tournament.

What are the biggest indicators of March Madness success? ›

  • Picking NCAA Tournament Winners. ...
  • March Madness Champions Rely on Upperclassmen. ...
  • March Madness Champions Are Guided by Proven Coaches. ...
  • March Madness Champions Have Great Point Guards. ...
  • March Madness Champions Finish in the Top 4 of the BPI. ...
  • March Madness Champions Come from Schools with Large Student Bodies.

Who is the best college basketball analyst? ›

Jay Bilas is ESPN's top college basketball analyst and is widely recognized for his thorough knowledge of the game and his professional, clever style.

What are the top teams favored to win March Madness? ›

March Madness Power Rankings: Final Four
  • T-3) North Carolina State Wolfpack (+1600) In the never-ending fight against fate, destiny always wins. ...
  • 2) Purdue Boilermakers (+205) Basketball may very well be the most superstar-driven sport in the world. ...
  • 1) UConn Huskies (-195)
Apr 2, 2024

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